ea0049ep696 | Obesity | ECE2017
O'Shea Donal
, Tobin Laura
, Cody Declan
, Mat Arimin
, Kinlen David
, Hogan Andrew
Abstract: Obesity has reached epidemic proportions globally. At least 2.8 million people die each year as a result of being overweight or obese, the biggest burden being obesity-related diseases. Glucagon like peptide 1 (GLP-1) targeted therapies show the greatest potential for intervention and are approved as weight loss agents. However not all patients respond to GLP-1 therapy. Understanding the mechanisms of bodyweight regulation and their role in GLP-1 responders vs. non-r...